A protein complex in beta cells that includes the Islet-1 transcription factor regulates genes important to develop and maintain functional beta cells. Now researchers report the complex also associates with enzymes RNF20 and RNF40, and disruption of either enzyme reduces insulin release.Article Correctness Is Author's Responsibility: New members found in a transcription factor complex that maintains beta cells
A protein complex in beta cells that includes the Islet-1 transcription factor regulates genes important to develop and maintain functional beta cells. Now researchers report the complex also associates with enzymes RNF20 and RNF40, and disruption of either enzyme reduces insulin release.
