Article Correctness Is Author's Responsibility: Scientists optimize prime editing for rice and wheat

(Chinese Academy of Sciences Headquarters) Recently, a research team led by Prof. GAO Caixia of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences reported the optimization of a prime editing system (PPE system) for creating desired point mutations, insertions and deletions in two major cereal crops, namely, rice and wheat. The main components of a PPE system are a Cas9 nickase-RT fusion protein and a pegRNA.